Data Management of Protein Interaction Networks

• Date de parution : 03/02/2012
• Editeur : Wiley-ieee Computer Society Pr
• EAN : 9781118103739
• Série : (-)
• Support : Livre numérique

• Nombre de pages : (-)
• Collection : (-)
• Genre : (-)
• Thème : Non attribué
• Prix littéraire(s) : (-)

Current PPI databases do not offer sophisticated querying interfaces and especially do not integrate existing information about proteins. Current algorithms for PIN analysis use only topological information, while emerging approaches attempt to exploit the biological knowledge related to... Voir plus

Current PPI databases do not offer sophisticated querying interfaces and especially do not integrate existing information about proteins. Current algorithms for PIN analysis use only topological information, while emerging approaches attempt to exploit the biological knowledge related to proteins and kinds of interaction, e.g. protein function, localization, structure, described in Gene Ontology or PDB. The book discusses technologies, standards and databases for, respectively, generating, representing and storing PPI data. It also describes main algorithms and tools for the analysis, comparison and knowledge extraction from PINs. Moreover, some case studies and applications of PINs are also discussed.